We are an interdisciplinary group of researchers working at the interface of biology, physics, and engineering sciences. We use quantitative experiments and mathematical modeling to answer fundamental questions in developmental, stem cell, and cancer biology.
10/11/2018 2d gastuloid patterning paper on bioRxiv
Our preprint on how BMP, WNT and Nodal combine to generate self-organized patterns is online now. link.
8/31/2018: Wnt signaling dynamics preprint on bioRxiv
Our paper examining signaling dynamics in pluripotency and differentiation is online now. link.
5/22/2018: Aryeh on Houston public radio:
You can hear the interview about human stem cell and embryo research here
5/17/2018: Synthetic secreted reporter preprint in bioRxiv
Our paper on using secreted synthetic small RNAs as non-destructive reporters is online in biorxiv. link.
4/1/2018: Welcome Elena!
Elena Camacho Aguilar has joined the lab as a postdoc
3/1/2018: Welcome Suparna!
Suparna Sarkar-Banerjee has joined the lab as a postdoc
2/21/2018: Welcome Kong and Miguel!
Xiangyu Kong and Miguel Angel Ortiz Salazar have joined the lab as PhD students
1/12/2018: New NIH grant
our lab has received an R01 grant to study Wnt signaling dynamics and ectodermal patterning. Rice press release is here.
11/16/2017: Nodal signaling dynamics preprint in bioRxiv
See our latest on how the dynamics of Nodal and BMP signaling are interpreted in stem cell patterning here: https://www.biorxiv.org/content/early/2017/10/13/202366
8/10/2017: Community effect paper published in Development
Our paper on morphogen and community effects in BMP-mediated differentiation is now published in Development. link
7/28/2017: Simons Investigator award
Aryeh has been named a Simons investigator in the Mathematical Modeling of Living Systems.